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Steven Nissen

A prominent Food and Drug Administration researcher sharply criticized a safety study by the manufacturer of the diabetes drug Avandia on Tuesday as an FDA panel weighed whether to yank the drug from the market.

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Avandia and diabetes: Was revolution worth the risks?updated: Fri Jul 09 2010 08:50:00

A decade after critics first accused the Food and Drug Administration of downplaying side effects from Avandia, the agency says it will reveal on Friday the data it is reviewing ahead of an advisory panel meeting about the safety of the popular diabetes drug.

FDA considers statin use for those with normal cholesterolupdated: Tue Dec 22 2009 11:57:00

Should people who don't have high cholesterol take a cholesterol-lowering statin? Maybe, according to the U.S. Food and Drug Administration, which is considering an advisory panel's recent recommendation to do just that.

Risks of daily aspirin may outweigh the benefitsupdated: Thu Nov 05 2009 11:38:00

Taking a low-dose aspirin every day can help prevent heart attacks in people who've already had one. But if you've never had a heart attack (or stroke), the risks of taking a daily low-dose aspirin outweigh the benefits, according to a U.K. report published in Drug and Therapeutics Bulletin.

Study: Cholesterol drugs could help those with healthy levelsupdated: Mon Aug 10 2009 14:46:00

Healthy men and women with good cholesterol levels could significantly reduce their risk of heart disease by taking cholesterol-lowering drugs, better known as statins, according to a study released at the American Heart Association meetings in November.

King: Cleveland Clinic pushes into futureupdated: Fri Jun 19 2009 15:10:00

As he walks the halls of the Cleveland Clinic, Dr. Steven Nissen makes the next generation of health care in America sound quite simple.

CNNMoney: Study: Mixed results on diabetes drug safetyupdated: Wed Sep 12 2007 00:58:00

Actos and Avandia have entered the spotlight again, as studies published in a leading medical journal pit the two diabetes drugs against each other by comparing their cardiovascular risks.

CNNMoney: Keep Avandia on market, say FDA advisersupdated: Mon Jul 30 2007 07:38:00

Food and Drug Administration panelists voted Monday that GlaxoSmithKline's diabetes drug Avandia should remain on the market, despite an analysis showing links to increased risk of heart attack.

CNNMoney: Glaxo prepares for face-to-face with FDAupdated: Fri Jul 20 2007 01:57:00

GlaxoSmithKline is getting ready for a face-to-face with the FDA about its diabetes drug Avandia, which has been on the hot seat since a study blamed the drug for increasing the risk of heart attack.

CNNMoney: Merck sees long-term benefits from Januviaupdated: Sat Jun 23 2007 02:58:00

Merck's new drug Januvia controls blood-sugar in two-thirds of diabetics when combined with the drug metformin, the company said Saturday.

Time.com: Is Avandia the Next Vioxx?updated: Fri May 25 2007 15:40:00

With concerns raised about heart risks of a popular diabetes drug, GlaxoSmithKline and the FDA scramble to respond

CNNMoney: Judgment day for new Merck painkillerupdated: Tue Apr 10 2007 13:35:00

The moment of truth has come for Arcoxia, Merck's arthritis painkiller intended to replace the withdrawn drug Vioxx.

CNNMoney: Lilly cholesterol trial misses the markupdated: Sun Mar 25 2007 16:39:00

An extremely potent experimental cholesterol drug being developed by Eli Lilly and Co. failed to show an advantage over an existing treatment sold by Abbott Laboratories Inc. in a clinical trial that could determine the fate of the medicine.

Heart disease still the most likely reason you'll dieupdated: Mon Oct 30 2006 13:00:00

It may be America's No. 1 killer, but people aren't scared enough of heart disease, says a top U.S. research cardiologist.

Cardiologist goes toe to toe with drug companiesupdated: Tue Nov 01 2005 12:05:00

As Dr. Steven E. Nissen methodically ticks off the risks of what seemed like a highly promising experimental diabetes drug -- heart attacks, strokes, and death -- he is completely in his element.

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